What are the applications of TQ series static multifunctional extraction tanks in the pharmaceutical
The TQ series static multifunctional extraction tank is a commonly used high-efficiency extraction equipment in the pharmaceutical field, mainly used for the extraction, concentration, separation and other operations of active ingredients in Chinese medicinal materials. The following are its main application scenarios and characteristics in the pharmaceutical field:
1、 Extraction process of tradi
The TQ series static multifunctional extraction tank is a commonly used high-efficiency extraction equipment in the pharmaceutical field, mainly used for the extraction, concentration, separation and other operations of active ingredients in Chinese medicinal materials. The following are its main application scenarios and characteristics in the pharmaceutical field:
1、 Extraction process of traditional Chinese medicinal materials
1. Water extraction
Application scenario: Suitable for extracting water-soluble components (such as glycosides, sugars, amino acids, organic acid salts, etc.), it is a commonly used process for traditional Chinese medicine decoctions, oral liquids, granules and other dosage forms.
characteristic:
The dissolution rate of water-soluble components can be improved by controlling the temperature (usually boiling or near boiling state) and time.
Supports extraction under normal or slight pressure, with high safety, suitable for medicinal materials with weak heat sensitivity.
2. Alcohol extraction (organic solvent extraction)
Application scenario: Used for extracting fat soluble components (such as alkaloids, volatile oils, flavonoids, steroids, etc.), commonly used in the preparation of tinctures, alcoholic beverages, and some injections.
characteristic:
Organic solvents such as ethanol can be used to increase the solubility of components through reflux extraction.
Equipped with a solvent recovery device to reduce costs and minimize environmental pollution.
3. Extraction of volatile oil
Application scenario: Extracting volatile oil components from traditional Chinese medicine (such as menthol, cinnamaldehyde, etc.) for use in aromatic drugs, essential oil preparations, or as active ingredients in Chinese herbal formulas.
characteristic:
The volatile oil is separated by steam distillation, and the equipment is equipped with condensation and oil-water separation devices to achieve efficient collection.
2、 Production and application of traditional Chinese medicine preparations
1. Preparation of Oral Liquid and Compound
Process: After extraction, filtration, and concentration of traditional Chinese medicine materials, they are added with flavoring agents, preservatives, etc. to make oral liquid preparations.
Advantages:
The extraction process can be automated to ensure batch stability.
Closed operation reduces component oxidation and preserves pharmacological activity.
2. Extraction of injection raw materials
Requirement: High purity and safety are required for extraction, and impurities (such as proteins, tannins, etc.) need to be removed.
Application:
Used for extracting effective ingredients of traditional Chinese medicine for intravenous or intramuscular injection (such as astragalus polysaccharides, tanshinone, etc.).
Through multi-stage filtration and purification processes, combined with temperature control and stirring functions of the extraction tank, clarity and safety are improved.
3. Preparation of raw materials for granules and tablets
Process: The extract is concentrated and dried to make a paste powder, which is used as the raw material for granules or tablets.
Equipment adaptability:
Extraction tank can be linked with concentrator and drying equipment (such as spray dryer) to form production line and improve production efficiency.
3、 Application of special extraction process
1. Combining dynamic and static extraction
Function: Some models of TQ series tanks support stirring function (static tanks usually do not have stirring, but can be upgraded through design), which can intermittently stir during the extraction process to enhance solid-liquid mass transfer efficiency. It is suitable for hard or viscous medicinal materials (such as resins and roots).
2. Low temperature extraction
Application scenario: Protective extraction of thermosensitive components (such as enzymes, peptides, vitamins, etc.), such as the production of certain biopharmaceuticals or natural medicines.
Operation method: By controlling the interlayer cooling medium (such as ice water or low-temperature saltwater), the extraction temperature is controlled in the low-temperature range (such as below 40 ℃) to avoid component degradation.
3. Switching between atmospheric pressure and pressurized extraction
Flexibility: The equipment can be controlled by valves to achieve normal pressure extraction (suitable for easily expanding medicinal herbs) or micro pressure extraction (increasing boiling point and shortening extraction time), adapting to the characteristics of different medicinal herbs.
4、 Equipment advantages and adaptability to the pharmaceutical industry
1. Multi functional integration
One device can complete various operations such as extraction, concentration, solvent recovery, distillation, etc., reducing equipment investment and process transfer losses.
2. Compliant with GMP standards
Made of stainless steel material (such as 304 or 316L), with polished inner walls to avoid material retention and contamination, meeting the requirements of Good Manufacturing Practice (GMP) for pharmaceutical production.
3. Automated control
Equipped with a monitoring system for temperature, pressure, time and other parameters, supporting manual or PLC automatic control, facilitating the recording and traceability of process parameters, ensuring the standardization of the production process.
4. Energy conservation and environmental protection
The solvent recovery system can reuse organic solvents to reduce emissions; Efficient heat exchange design reduces energy consumption and conforms to the concept of green pharmaceuticals.
5、 Typical application cases
Case 1: A traditional Chinese medicine enterprise uses the TQ-500 extraction tank to produce Shuanghuanglian oral liquid. The effective ingredients in honeysuckle, Scutellaria baicalensis, and Forsythia suspensa are extracted through water extraction technology, and then concentrated and purified with alcohol to produce semi-finished products. The annual output can reach millions of tubes.
Case 2: A certain herbal medicine company used the TQ-1000 extraction tank to extract volatile oils from medicinal herbs such as roses and lavender. Aromatic oils were separated and used to prepare topical ointments and traditional Chinese medicine sachets. The extraction efficiency was improved by 30% compared to traditional processes.
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